Publications

Zikry TM, Wolff SC, Ranek JS, Davis HR, Naugle A, Luthra N, Whitman AA, Kedziora KM, STALLAERT W, Kosorok MR, Spanheimer PM & Purvis JE. (2023). Cell cycle plasticity underlies fractional resistance to palbociclib in ER+/HER2- breast tumor cells. PNAS. 121(7): e2309261121.

Kedziora KM and STALLAERT W. (2024). Cell cycle mapping using multiplexed immunofluorescence. Methods Mol Biol. 2740:243-262. Preprint available here

STALLAERT W, Taylor SR, Kedziora KM, Johnson MS, Taylor CM, Sobon HS, Young CL, Limas JC, Cook JG & Purvis JE. (2022). The molecular architecture of cell cycle arrest. Molecular Systems Biology . 18:e11087. Full text

STALLAERT W, Kedziora KM, Taylor CM, Zikry TM, Ranek JS, Sobon HS, Taylor SR, Young CL, Cook JG & Purvis JE. (2022). The structure of the human cell cycle. Cell Systems, 13(3): 230-240. Full text

Enrico TP, STALLAERT W, Wick ET, Ngoi P, Rubin SM, Brown NG, Purvis JE & Emanuele MJ (2021). Cyclin F drives proliferation through SCF-dependent degradation of the retinoblastoma-like tumor suppressor p130/RBL2. eLife, 10:e70691. Full text

Brüggemann Y, Karajannis LS, Stanoev A, STALLAERT W & Bastiaens PIH (2021). Growth factor– dependent ErbB vesicular dynamics couple receptor signaling to spatially and functionally distinct Erk pools. Science Signaling, 14(683). Full text

STALLAERT W, Kedziora KM, Chao HX & Purvis JE (2019). Bistable switches as integrators and actuators during cell cycle progression. FEBS letters, 593(20): 2805-2816. Full text

STALLAERT W, Brüggemann Y, Sabet O, Baak L & Bastiaens PIH (2018). Contact inhibitory Eph signaling suppresses EGF-promoted cell migration by decoupling EGFR activity from vesicular recycling. Science Signaling, 11(541). Full text

Stanoev A, Mhamane A, Schuermann KC, Grecco HE, STALLAERT W, Baumdick M, Bruggemann Y, Joshi MS, Roda-Navarro P, Fengler S, Stockert R, Rossmannek L, Luig J, Koseska A & Bastiaens PIH (2018). Interdependence between EGFR and phosphatases spatially established by vesicular dynamics generates a growth factor sensing and responding network. Cell Systems, 7(3): 295-309. Full text

Schönegge A-M, Gallion J, Picard L-P, Wilkins AD, Le Gouill C, Audet M, STALLAERT W, Lohse MJ, Kimmel M, Lichtarge O & Bouvier M (2017). Evolutionary activation and structural basis of the allosteric switch controlling β2AR functional selectivity. Nature Communications, 87(1): 2169. Full text

STALLAERT W, van der Westhuizen ET, Schönegge A, Plouffe B, Hogue M, Lukashova V, Inoue A, Ishida S, Aoki J, Le Gouill L, and Bouvier M (2017). Purinergic receptor transactivation by the β2 adrenergic receptor increases intracellular Ca2+ in non-excitable cells. Molecular Pharmacology, 91(5):533-544. Full text

Thanawala VJ, Forkuo GS, STALLAERT W, Leff P, Bouvier M and Bond R (2014). Ligand bias prevents class equality among beta-blockers. Current Opinion Pharmacology, 16:50-57. Full text

STALLAERT W, Dorn JF, van der Westhuizen E, Audet M, Bouvier M (2012). Impedance Responses Reveal β2-Adrenergic Receptor Signaling Pluridimensionality and Allow Classification of Ligands with Distinct Signaling Profiles. PLoS One, 7(1): e29420. Full text

STALLAERT W, Christopoulos A, and Bouvier M (2012). Ligand functional selectivity and quantitative pharmacology at G protein-coupled receptors. Expert Opinion on Drug Discovery, 6(8):811-825.